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It is an anatase titanium dioxide pigment produced by a special process from sulfuric acid. Widely used in PVC pipes, interior coatings, industrial pigments, rubber, leather, polyolefins, Printing ink, plastic, paper, etc.

Zhu et al. were the first to provide evidence that TiO₂ NPs (21 nm) can transfer from daphnia to zebrafish by dietary exposure. Hence, dietary intake could be a major route of exposure to NPs for high trophic level aquatic organisms. Ecological research should therefore focus, not only on the concentration of NPs in the environment, but also on its bioconcentration, bioaccumulation and biomagnification. In addition it has been shown that TiO₂ NPs can increase accumulation of other environmental toxicants: enhanced accumulation of cadmium (Cd) and arsenic (As) was found in carp in the presence of TiO₂ NPs. The strong adsorption capacity for Cd and As was explained by the large specific surface area and strong electrostatic attraction of TiO₂ NPs that contribute to facilitated transport into different organs.

Lithopone is a white pigment (PW5) co-precipitated from solutions of zinc and barium salts according to the following reaction: