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It's important to note that while chili peppers offer potential health benefits, individual responses to spicy foods can vary. Some people may experience digestive discomfort or irritation from consuming chili peppers, particularly in large amounts. As with any dietary component, it's best to consume chili peppers in moderation as part of a balanced diet.

In rare cases, allergic reactions to paprika and bell peppers can occur, causing symptoms such as hives, itching, swelling, and difficulty breathing. Individuals who experience these symptoms after consuming paprika or bell peppers should seek medical attention immediately.