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The biological significance of the double helical structure is perhaps most evident in the DNA molecule. Discovered by James Watson and Francis Crick in 1953, the double helix model revolutionized our understanding of genetics Discovered by James Watson and Francis Crick in 1953, the double helix model revolutionized our understanding of genetics Discovered by James Watson and Francis Crick in 1953, the double helix model revolutionized our understanding of genetics Discovered by James Watson and Francis Crick in 1953, the double helix model revolutionized our understanding of geneticsdouble helical spring. DNA, the blueprint of life, contains two complementary strands that wind around each other like a twisted ladder, forming the double helix. These strands are held together by hydrogen bonds, ensuring the stability and fidelity of genetic information.