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The viscosity of hydroxyethyl cellulose is directly related to its concentration in a solution. Generally, as the concentration of HEC increases, the viscosity of the solution also rises. This is due to the increased number of polymer chains that entangle and interact with each other, creating a more viscous system. The behavior of HEC solutions can be described by the principle of entanglement, where higher concentrations lead to a complex network formation among the polymer chains.
Pagkatapos ng alkalisasyon, ang cellulose ay hinaluan ng ethylene oxide (EO), isang reaktibong kemikal na nagdadala ng hydroxyethyl groups. Sa pamamagitan ng pagkokontrol sa temperatura at presyon sa panahon ng reaksyon, ang mga hydroxyethyl groups ay ikinakabit sa cellulose backbone. Ang proseso ng rekomendasyon ay nagsisimula sa mga temperatura sa pagitan ng 40-60 degrees Celsius, at kadalasang tumatagal ng ilang oras, depende sa nais na degree of substitution (DS) ng HEC.
hydroxyethyl cellulose synthesis

Moreover, hypromellose is an essential ingredient in ophthalmic preparations, particularly in eye drops. Its excellent mucoadhesive properties help retain moisture on the eye's surface, alleviating dry eye symptoms. As a result, HPMC has become a preferred choice for the formulation of artificial tears and other ocular solutions.
hypromellose hpmc
