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if you compare the levels—which went as high as 50,000 milligrams/killigrams per day— to what humans are actually exposed to, we're talking orders of magnitude. It was a huge amount, Norbert Kaminski, PhD, a professor of pharmacology & toxicology and director of the Center for Research on Ingredient Safety at Michigan State University told Health.

Because of health risks, France banned titanium dioxide as a food additive in 2020. Two years later the European Union also banned titanium dioxide as a food additive. 

Titanium dioxide is predominantly used as a pigment in products such as paints, coatings, plastics, food, cosmetics, and paper. The ability of TiO2 to scatter light and provide a white color makes it an essential ingredient in achieving high-quality finishes in these applications. However, the production of titanium dioxide can be complex and costly, given that it involves raw materials such as ilmenite and rutile, as well as advanced processing technologies. Manufacturers are continuously striving to optimize costs without compromising quality, making the search for affordable suppliers a top priority for many businesses.