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Chemical Properties and CAS Number

Hydroxypropyl methylcellulose (HPMC), also known as hypromellose, is a versatile and widely used cellulose derivative. It is derived from cellulose, a natural polymer found in plants. HPMC is synthesized by treating cellulose with propylene oxide and methyl chloride, which creates a water-soluble and biodegradable polymer.

HPMC is a non-ionic cellulose ether produced from natural cellulose. Through a series of chemical modifications, cellulose is altered to introduce hydroxypropyl and methoxy groups, which enhance its solubility in water and its functional properties. HPMC is primarily known for its thickening, emulsifying, and film-forming abilities, making it an essential ingredient in many formulations.

Conclusion

HEC is derived from cellulose through a chemical reaction involving ethylene oxide. This modification introduces hydroxyethyl groups, enhancing its solubility in water and creating a versatile polymer that can function as a thickening agent and stabilizer in various formulations. HPMC, on the other hand, is produced by the partial methoxylation and propoxylation of cellulose, resulting in a product that is highly soluble and has unique gel-forming properties. These chemical differences lead to varying degrees of water retention, viscosity, and gel strength, which can significantly impact the performance of pharmaceutical formulations.

Applications in Pharmaceuticals