square ironing board cover_pumpkin tablecloth
In addition to its physical properties, the density of HPMC also plays a significant role in its solubility and viscosity. The higher density of HPMC allows it to dissolve more easily in water, making it a popular choice for use in pharmaceuticals, food products, and cosmetics. The viscosity of HPMC solutions can also be easily adjusted by changing the density of the polymer, allowing for greater control over the flow and consistency of the final product.
hpmc density

Molecular weight also plays a pivotal role in determining HPMC's solubility. Lower molecular weight HPMC is generally more soluble in organic solvents than its high molecular weight counterparts due to the reduced entanglement of polymer chains. This characteristic can be particularly important during the processing of drug formulations, where the solubility and viscosity of HPMC can significantly impact the release profile of the active pharmaceutical ingredient (API).
hpmc solubility in organic solvents

Inhalation of hydroxypropyl methylcellulose dust—often a risk in industrial settings—can lead to respiratory problems such as coughing, wheezing, and shortness of breath
. People with pre-existing respiratory conditions, such as asthma or chronic obstructive pulmonary disease (COPD), should take caution when around airborne HPMC and consider using protective measures, such as masks or respirators, if working in environments where dust is prevalent.