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The pricing of lithopone pigments can fluctuate based on several factors, including raw material costs, production processes, and market demand. Typically, wholesale prices reflect the bulk purchasing power, enabling businesses to acquire these materials at a lower cost per unit. Over the years, the market has seen fluctuations in prices due to changes in the supply chain and global economic conditions. It is crucial for buyers to stay informed about these trends to budget effectively and maintain profitability.

The risks associated with titanium dioxide exposure depend on a variety of factors, including the form of the mineral, the route of exposure (such as being inhaled or consumed), and the duration and intensity of exposure.

In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.