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HPMC plays a critical role in the pharmaceutical sector, particularly as an excipient in drug formulations. It is widely utilized in tablet manufacturing, where it aids in controlling the release of active ingredients, making it an excellent material for sustained-release formulations. HPMC can also be found in capsule formulations, as it is a suitable vegetarian alternative to gelatin. The property of being hygroscopic allows it to maintain the moisture content of tablets, thereby extending their stability and shelf-life. Moreover, HPMC is employed in ocular solutions, providing viscosity to eye drops, ensuring better adherence to the eye surface and enhancing the therapeutic effect.
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According to toxicological research, HPMC has a low potential for toxicity, and there are no significant concerns regarding its use. Studies indicate that HPMC does not cause mutagenic, carcinogenic, or reproductive toxicity effects in living organisms. Additionally, HPMC is non-allergenic for the majority of individuals, meaning it rarely triggers allergic reactions.
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