Methyl cellulose and HPMC are both cellulose-based polymers, meaning they are nearly identical in chemical composition and structure. The main difference between the two is that HPMC has been modified with hydroxpropyl groups. HPMC is more water soluble and is therefore used in more industries than methyl cellulose. Methyl cellulose is more commonly used in food and cosmetics, while HPMC is more commonly used in pharmaceuticals and construction. In terms of application, however, there is very little difference between methyl cellulose and HPMC.

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