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In conclusion, wholesale lithopone MSDS quotes play a crucial role in ensuring the safe and responsible use of this important industrial pigment. By considering key factors such as product information, hazard identification, safety measures, emergency procedures, and regulatory compliance, businesses can make informed decisions when sourcing lithopone for their manufacturing processes. Ultimately, prioritizing safety and regulatory compliance is essential for a successful and sustainable industrial supply chain.

TiO₂ NPs appeared to be more toxic to nematode Caenorhabditis elegans than submicron-sized TiO_2.  At a concentration of 1 mg/l, 7 nm particles affected its fertility and survival rate and were more toxic than 20 nm anatase particles. Similarly, Hu et al. showed that rutile particles (10–20 nm), at concentrations above 1 g/kg soil, can be bio-accumulated in earthworms, where they induce oxidative stress, inhibit the activity of cellulase and induce DNA and mitochondrial damage.

Most notably, a European Food Safety Authority safety assessment published in May 2021 pointed to genotoxicity concerns, as suggested by previous research. Genotoxicity is the ability of chemicals to damage genetic information such as DNA, which may lead to cancer.

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