According to the EFSA's Expert Panel on Food Additives and Flavorings 2021 opinion regarding titanium dioxide, it could not rule out a concern for genotoxicity from ingestion of the material based on a perceived gap in data on this risk, which serves as the basis for current ban, said a March report on the decision.
Food additive or carcinogen? The growing list of chemicals banned in EU but used in US, by Mikaela Conley, The Guardian, June 23, 2022