A 2012 study published in the journal Environmental Science & Technology noted that children are especially exposed to titanium dioxide because of the food that contains the food additive and is particularly marketed to children, including candy and cakes.
Here it has been shown that functionalization of P25TiO2NPs with vitamin B2 was able to significantly decrease the oxidative stress produced when they are exposed to sunlight. This finding is of main importance to prevent skin damage and toxicity of sunscreens containing this form of untreated titanium dioxide and should be taken into consideration when updating the regulations mentioned above .