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Titanium dioxide nanoparticles have also been found in human placentae and in infant meconium, indicating its ability to be transferred from mother to fetus. 

The FDA's Code of Federal Regulations allows for the legal, regulated use of titanium dioxide in food products, under some restrictions.

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As a food additive, titanium dioxide and its nanoparticles in particular have been associated with DNA damage and cell mutations, which in turn, have potential to cause cancer. When used as a food coloring, it is known as E171.