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In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.

Lithopone

In terms of application, meticulous preparation and attention to detail yield the best results. For paint grinders, maintaining a ratio of 12 pounds of refined linseed oil to 88 pounds of lithopone pigment will provide optimal workability. A salient factor that should be heeded is the state of the lithopone before mixing with oil; the material must be sufficiently dry. Only then will it integrate seamlessly with the oil, ensuring that the resultant mixture possesses the desired consistency and properties.