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Most countries have their own variety of chili peppers, ranging from poblano, serrano, Tabasco, jalapeno, peri-peri, habanero, cayenne and numerous others. Originating in Mexico, the red chili made its way across the world and is used in many cuisines. Many varieties may also be used fresh and green or red or pickled instead of dried and powdered.

Curcumin has been approved by the US Food and Drug Administration as a soothing compound. The recommended extreme daily doses range is from 3 mg/kg to 4-10 g/day. Since most studies using the extract have a time limit of 1-3 months, to date, there is no evidence of any long-term consequences from long-term use of curcumin. Although there have been no reports of serious adverse reactions to curcumin use, some side effects may include diarrhea, head pain, skin rashes, and yellow stools.