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At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.

Some dealers quoted prices that were significantly higher than expected, sending the domestic market to an almost three-year high. Meanwhile, a similar scenario was observed in the Indian market, where titanium dioxide prices (rutile grade) for rose by 8% from January to March. The increase was attributed to strong demand from the domestic paints and coatings sector as well as premium cargo from China.