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Recent analyses of food-grade TiO₂ samples have found that a significant portion of particles may be within the nanoscale. These particles (also known as nanoparticles) range in size from 1 to 100 nm, where 1 nm equals 1 billionth of a metre (the width of a typical human hair is 80,000 to 100,000 nm).

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While Skittles don't include white in their line-up, Dr. Johnson-Arbor theorizes that titanium dioxide is used to help contain all the other beautiful colors.