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In addition to its culinary applications, paprika oleoresin is also used in the pharmaceutical and cosmetic industries for its colorant properties. It provides a natural alternative to synthetic food colorants and is valued for its stability and resistance to fading.

Despite the potential for allergic reactions, paprika and bell peppers have been found to have therapeutic uses. Capsaicin, a compound found in peppers, has been shown to have analgesic properties and is commonly used in musculoskeletal pain therapies. Capsaicin can be applied topically to the skin to alleviate pain and reduce inflammation.