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In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon.  There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”

Durabo White, 24.5 per cent zinc sulphide, 51 per cent barium sulphate, 18 per cent white clay, 5.5 per cent infusorial earth.

It's also added directly to food; mainly for coloring, but also as a thickener and to keep some powdered food, like confectioner's sugar, from clumping.   

Food containing titanium dioxide that is lawfully placed on the EU market before 7 August 2022 may remain on the market until its date of minimum durability or its ‘use-by’ date has passed. Food produced or placed on the market after 7 August 2022 cannot contain titanium dioxide. The ban on the use of titanium dioxide is effective in each EU Member State, and in Northern Ireland. Some third countries, such as the United Kingdom (excluding Northern Ireland), continue to permit the use of titanium dioxide.

When choosing lithopone, you must choose a good brand and pay attention to its production date. Some people just don’t pay attention to this aspect and often pursue cheap prices. As a result, they buy products that are close to their expiration date and have not been stored for long. It is no longer usable. This is very important.