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Titanium dioxide nanoparticles have also been found in human placentae and in infant meconium, indicating its ability to be transferred from mother to fetus. 

The EU expert panel did not identify an immediate health concern linked to TiO₂ when used as a food additive. However, due mainly to uncertainties concerning the safety of TiO₂ nanoparticles, the panel concluded that TiO₂ as a food additive (E171) could no longer be considered safe.

Research supports that applying titanium dioxide to the skin in the form of sunscreens, makeup, and other topical products does not pose any health risks.