Intraocularly, hpmc is used as a volume substitute for the aqueous humor to maintain anterior segment integrity and anatomical spaces during intraocular interventions, to protect intraocular tissues (i.e. the corneal endothelium), to sustain corneal transparency as well as for the lubrication of intraocular lenses (IOL) and surgical instruments.
2)The viscosity of Hydroxypropyl Methylcellulose is influenced by its molecular weight, with higher molecular weight leading to higher viscosity. Temperature also affects its viscosity, with viscosity decreasing as temperature rises. However, the impact of temperature on viscosity is lower compared to Methyl Cellulose. Its solution is stable when stored at room temperature.