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Titanium dioxide is considered safe for use in cosmetics products by expert bodies around the world, including Europe's Scientific Committee on Consumer Safety (SCCS) and the U.S. Food and Drug Administration (FDA). Nano grade titanium dioxide has been assessed by the SCCS and is approved by the European Commission for use as a UV filter.

Because of health risks, France banned titanium dioxide as a food additive in 2020. Two years later the European Union also banned titanium dioxide as a food additive.