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Titanium dioxide nanoparticles are commonly found in a wide-range of consumer goods, including cosmetics, sunscreens, paints and colorings, ceramics, glass, textiles, construction materials, medicine, food, food packaging, and more. In Europe, cosmetic companies are required to label products that contain nanoparticles. In the U.S., companies are not.

In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.