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Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

FAQ
Q1. Can I have a sample order for Titanum Dioxide?
A: Yes, We can express you 500 grams of samples, free of charge. And the quality is subject to the sample.

Q2. What about the lead time?
A: Within 15days after receiving the payment

Q3. Do you have any MOQ limit for Titanium Dioxidde?
A: 5MT

Q4. Is it OK to print my logo on the Titanium Dioxide Packing bag?
A: Yes. Please inform us formally before our production and confirm the design LOGO firstly.

Q5: What's the payment term?
A: T/T or L/C at sight

Manufacturers get titanium dioxide from minerals called brookite, rutile, and anatase. It's processed into a powder and refined to meet strict safety guidelines.