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Firstly, the cellulose is treated with alkali, usually sodium hydroxide, to create a cellulose alkali solution. This step, known as alkalization, makes the cellulose more reactive. Next, the alkali cellulose is reacted with a propylene oxide and methylation agent, typically in the presence of a solvent like acetone or ethyl alcohol. Propylene oxide adds hydroxypropyl groups to the cellulose structure, while methylation is achieved through the action of methyl chloride. These modifications alter the properties of cellulose, imparting it with water-solubility and other desirable characteristics These modifications alter the properties of cellulose, imparting it with water-solubility and other desirable characteristics These modifications alter the properties of cellulose, imparting it with water-solubility and other desirable characteristics These modifications alter the properties of cellulose, imparting it with water-solubility and other desirable characteristicswhat is hpmc made from.

The quality of HPMC dispersion is often measured by parameters such as viscosity, clarity, and sedimentation ratehpmc dispersion. A well-dispersed HPMC solution should exhibit consistent viscosity over time, be free from visible particles, and have minimal settling. The right balance of HPMC concentration, hydration temperature, and mixing conditions can optimize these properties.