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The production of HPMC is characterized by controlling the degree of substitution and the molecular weight. The degree of substitution refers to how many of the hydroxyl groups in the cellulose molecule have been replaced by methyl and hydroxypropyl groups. This parameter influences the water solubility and viscosity of HPMC. For instance, HPMC with a higher degree of substitution and molecular weight tends to have better thickening properties and higher gel strength, making it appealing for various applications.
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In pharmaceuticals, HPMC serves as a film-forming agent, tablet binder, and controlled-release formulation excipient. Its ability to regulate the release of active substances makes HPMC a critical component in modern drug delivery systems. This capability is particularly beneficial for patients, as it helps maintain consistent medication levels in the bloodstream, improving overall therapeutic efficacy.
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