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Paprika and bell peppers belong to the same family of plants, but they have distinct physical characteristics that set them apart. Here are some of the key differences:

Another option is to use a spice blend or a spice rub because these may contain large amounts of paprika. Cajun and Creole seasonings, for example, are mainly paprika along with garlic, thyme, salt, pepper, and cayenne, so you could certainly substitute one for the other. Similarly, Old Bay seasoning is mainly celery salt and paprika. As in the cases above, go with a 1:1 ratio.