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Sodium bicarbonate has some notable medicinal applications as well. It is often used in slightly alkaline solutions to treat conditions like heartburn and indigestion by neutralizing excess stomach acid. Additionally, it can be part of treatments for metabolic acidosis, where the body accumulates excess acid.

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Despite its popularity, aspartame has not been without its detractors. Some studies have raised concerns about its safety, linking it to various health issues ranging from headaches to more serious ailments. However, these claims have been extensively studied by food safety authorities worldwide, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). Both organizations have concluded that aspartame is safe for human consumption within established daily intake limits.