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They differ, while chili powder and paprika originate from chili peppers. Paprika is a singular spice with variations in flavor, while chili powder is a blend of several spices, offering a more complex flavor profile. Cayenne stands out for its heat, adding a spicy kick to any dish.

This recipe for spicy garlic sauce is addicting as is, but if you want to experiment, I have listed a few ideas below to try.

Because paprika and cayenne come from peppers, both can technically trace their roots back to the Americas. However, the two spices don’t come from the same kind of pepper—nor are they prepared the same way.

Substitute for Hot Smoked Paprika

However, they are very different spices, with a very different flavor profile, taste and usage. Let us see how they are different and how they are similar.