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In general, nanoparticles have been shown to accumulate in the body, particularly in organs in the gastrointestinal tract, along with the liver, spleen, and capillaries of the lungs.

Lithopone(CAS NO.1345-05-7) is manufactured by a process in which barium sulfide solution is prepared by reducing barite ore (BaSO4) with carbon and leaching the resulting mass.