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Research has shown that, when ingested as a food additive, titanium dioxide and its nanoparticles can impact, alter, and/or damage important protective bacteria in the gut, along with the metabolic pathways of gut bacteria.

④ Ink industry: titanium dioxide is also an indispensable white pigment in advanced ink. The ink containing titanium dioxide is durable and does not change color, has good surface wettability and is easy to disperse. The titanium dioxide used in the ink industry includes rutile and anatase.

TiO₂ absorbs UV light. This property makes it appear bright white under light, unlike other white materials that can look slightly yellow.