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What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.

However, since it’s photosensitive — meaning it can stimulate free radical production — it’s usually coated in silica or alumina to prevent potential cell damage without reducing its UV-protective properties (7Trusted Source).