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1. Gastrointestinal Upset One of the most common side effects of theophylline is gastrointestinal distress, which can manifest as vomiting, diarrhea, or a loss of appetite. These symptoms can be distressing for both the dog and the owner, but they often subside once the dog's system adjusts to the medication or the dosage is adjusted by a veterinarian.
The United States, while not leading in the overall production volume, remains a critical player in high-value APIs, particularly those that involve complex synthesis or advanced biotechnological processes. The U.S. regulatory environment, spearheaded by the Food and Drug Administration (FDA), imposes stringent guidelines on manufacturing practices. As a result, U.S.-produced APIs often carry premium pricing, reflecting their quality and reliability. The U.S. also invests heavily in research and innovation, focusing on the development of novel drugs and advanced therapeutics, which further drives API innovation.
active pharmaceutical ingredient production by country
