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Ajinomoto, a Japanese company, is perhaps the largest manufacturer of aspartame globally. With a solid presence in the natural and artificial sweetener markets, Ajinomoto has invested heavily in research and innovation to improve the quality and safety of its products. Recognizing the importance of sustainability, Ajinomoto has also focused on creating a supply chain that minimally impacts the environment while satisfying the growing global demand for low-calorie sweeteners.

Regulatory authorities, including the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA), have evaluated E471 and deemed it safe for use in food products. These organizations continue to monitor and review the latest scientific research to ensure consumer safety.

Moreover, they are often used in combination with other ingredients to enhance flavors, making foods more palatable without adding to the caloric burden that sugar typically imposes. This synergistic effect can make it easier for consumers to stick to healthier eating patterns.