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However, as with many food additives, there are some considerations regarding its consumption. Excessive intake of phosphates, including SAPP, has been linked to certain health concerns, particularly in individuals with kidney disorders. Therefore, it is vital for consumers, especially those on restricted diets, to be aware of their overall phosphate intake.

Once ammonia and carbon dioxide are available, they are combined in a reactor vessel in a controlled environment. The reaction between these two gases produces ammonium carbamate, an intermediate compound that subsequently decomposes to form ammonium bicarbonate. This reaction is exothermic, meaning it releases heat, which must be carefully managed to prevent overheating and maintain optimal production conditions.

One of the significant advantages of E365 compared to synthetic dyes is its natural origin. Many consumers today prefer food products that contain natural ingredients as part of a broader trend towards healthier eating. This preference for natural additives has led manufacturers to seek alternatives and enhance formulations that meet consumer expectations while ensuring safety and compliance with regulations.