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Moreover, the region of sourcing can also impact pricing. Suppliers in different geographical locations may offer varied prices due to differences in transportation costs, availability of raw materials, and local market conditions. Buyers must consider these regional variances when negotiating prices and establishing long-term relationships with suppliers. In many cases, sourcing from manufacturers that can produce high-quality lithopone pigments at competitive rates can lead to significant cost savings.

Overall, the Food Directorate's comprehensive review of the available science of TiO₂ as a food additive showed:

A number of our toothpastes do not contain titanium dioxide, including some of our Signal products (Signal Bio, Signal Nature Element, Signal White System, Signal Kids (Baby & Junior), Signal White Now Detox, Signal Anti-Cavity), Love Beauty and Planet and Schmidt’s Naturals.

≥100

How do I know if a Unilever product contains titanium dioxide?