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TiO₂ has been well accepted in the food industry and can be found as the E171 additive in various food products, mainly for whitening and texture. It is present in some cottage and Mozzarella cheeses, horseradish cream and sauces, lemon curd, and in low-fat products such as skimmed milk and ice-cream. Even if the product is labelled as containing E171, no information is usually given about the quantity, particle size and particle structure. FDA claims that TiO₂ may be safely used as a colour additive for colouring foods in quantities up to 1 % by weight of the food. Interestingly, TiO₂ is frequently declared as a “natural colouring agent” and is therefore well accepted by consumers.

Anyway, it doesn't matter if it reflects or absorbs, Titanium Dioxide is a pretty awesome sunscreen agent for two main reasons: it gives a nice broad spectrum coverage and it's highly stable. Its protection is very good between 290 - 350 nm (UVB and UVA II range), and less good at 350-400 nm (UVA I) range. Regular sized Titanium Dioxide also has a great safety profile, it's non-irritating and is pretty much free from any health concerns (like estrogenic effect worries with some chemical filters).

This cytotoxic effect was also reported before; i.e. Natarajan et al. conducted an experiment that found a strong oxidative stress, morphological changes in mitochondria and substantial loss in the fusion of primary hepatocytes exposed to P25TiO₂NPs [52].