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PTFE, which is used in the well-known brand Teflon®, is less commonly used, but it is the preferred material for specific rotating seals in the chemical, food and pharmaceutical industries. This material is notable for having a very low frictional resistance and the best chemical resistance. It can also withstand a very wide range of temperatures in these types of seals; -80 ˚C to 200 ˚C. The shafts on which oil seals with PTFE lips are used require a harder and finer finish. Something like an axle sleeve can also be used to meet this requirement.

Lubricants applied between moving and stationary elements of mechanical equipment help to prevent damage. But when the equipment are under high pressure, the lubricants tend to escape, hence the need for oil seals to prevent the clashing of dry parts. Practically all mechanical equipment, including car engines, assembly machines, and PTFE machined parts use these oil seals to prevent harmful interaction that can result in damaged parts.