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Hemolysis was studied on suspensions of P25TiO₂NPs (0.2 mg/mL and 0.02 mg/mL), vitaminB2@P25TiO₂NPs (0.2 mg/mL and 0.02 mg/mL) and vitamin B2 (0.2 mg/mL and 0.02 mg/mL) were prepared and mixed with 500 μL of anticoagulated blood (donated by Laboratorio de Hemoderivados, UNC) in a rate of 1/10. A solution of NaCl 10% was used as the positive control and PBS as the negative control. Then, the samples were irradiated using the LED described above for 3 and 6 h to simulate the light penetration into the skin. Also, a set of samples was kept in the dark as control. Finally, the samples were centrifuged and the absorbance at 540 nm was measured in the supernatants. The experiment was reproduced twice; the standard deviation was calculated and p-value < 0.05 were considered significant.

According to the feedback of manufacturers, the recent mainstream factory new single price, the market as a whole into the center of gravity. On the demand side, the terminal in August is still the off-season, many downstream still have inventory use, the current batch purchase intention is limited, and the market turnover is low. Some plastics and papermaking related downstream feedback part of the signal price is high. Recent titanium dioxide raw material price shock is strong, titanium dioxide price upward support has been enhanced, comprehensive market factors, the current titanium dioxide market into the stable price state after rising.