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Our scientific experts applied for the first time the 2018 EFSA Scientific Committee Guidance on Nanotechnology to the safety assessment of food additives. Titanium dioxide E 171 contains at most 50% of particles in the nano range (i.e. less than 100 nanometres) to which consumers may be exposed.  

Although cosmetics are not meant for consumption, there are concerns that titanium dioxide in lipstick and toothpaste may be swallowed or absorbed through the skin.