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In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.

Lithopone is produced by coprecipitation of barium sulfate and zinc sulfide. Most commonly coprecipitation is effected by combining equimolar amounts of zinc sulfate and barium sulfide:

You may be taking a second look at your favorite candy after hearing this week's news about titanium dioxide. Recently, a lawsuit was filed against Mars, Inc. based on claims that the manufacturer's popular Skittles candy is unfit for human consumption. The class-action lawsuit, filed in U.S. District Court for the Northern District of California in mid-July, alleged that the candy contained heightened levels of a known toxin called titanium dioxide — a food additive that the company previously pledged to phase out from their products in 2016, according to the Center for Food Safety.