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Sodium benzoate is generally recognized as safe (GRAS) when used in appropriate concentrations, specifically below 0.1% in food products. Regulatory bodies, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA), have evaluated its safety. However, it is imperative for consumers to be aware that in rare cases, when combined with ascorbic acid (vitamin C) and exposed to heat and light, sodium benzoate can form benzene, a known carcinogen. Due to this potential reaction, the use of sodium benzoate is monitored carefully in food products.

In laboratories, concentrated glacial acetic acid is an indispensable reagent. It is often utilized in the synthesis of various organic compounds and serves as a solvent for reactions where a strong acid is required. Furthermore, it is used in titrations to determine the concentration of bases or other alkaline substances. Its role as a dehydrating agent in organic synthesis is also noteworthy, particularly in the production of anhydrides and acetates.