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Pronounced as “gwaa-hee-oh“, guajillo is hotter than ancho chili powder and brings a spicy kick that ranges from 2,500 to 5,000 SHU. Apart from its spicy taste, this substitute has a lot more going on in flavor than cayenne. It is pleasingly sharp, tangy, and smoky just like paprika. That is why it’s also a good substitute for both hot and smoked paprika.

When used in food and pharmaceutical products, capsaicin oleoresin is generally considered safe when used in accordance with regulatory guidelines and recommended usage levels. However, individuals with known sensitivities or allergies to chili peppers should exercise caution, and it's important to ensure the purity and quality of the product.