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While HPMC is generally considered safe, some people may experience mild side effects, especially when consumed in high doses. These side effects may include gastrointestinal discomfort, bloating, or diarrhea. However, these effects are usually mild and short-lived and disappear once supplementation is stopped or the dose is reduced.

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The present assessment is based on data submitted by the applicant in the form of a technical dossier5 in support of the authorisation request for the use of HPMC as a feed additive.

Uses of Hydroxypropyl Methylcellulose:

Due to its excellent mucoadhesive properties, HPMC gel is used in ophthalmic solutions to provide longer residence time on the ocular surface and improve drug absorption.